Restore, repair, and regenerate your skin at a cellular level with Polynucleotide injections at Skin Redefined. This next-generation skin treatment goes beyond hydration and surface-level results — working deep within your skin to stimulate regeneration, collagen repair damaged cells, and improve overall skin health.
Polynucleotides are biostimulating injectables made from fragments of purified DNA. Unlike dermal fillers, which add volume, or skin boosters, which hydrate, Polynucleotides actively repair and regenerate your skin from within.
They work by:
In short, Polynucleotides don’t just make your skin look better, they actually make it function better.
Traditional skin boosters (like hyaluronic acid) provide hydration and a dewy glow, but their effects are often temporary. Polynucleotides go much further, actively repairing DNA damage, encouraging long-term collagen production, and tackling issues linked with ageing, sun exposure, and inflammation.
This makes them especially effective for concerns like fine lines, wrinkles, under-eye bags, and crepey or sagging skin — areas where standard boosters may not deliver enough improvement.
Polynucleotides can be used anywhere you have skin, this includes upper and lower eyelids which is generally a no-go area when it comes to most injectable treatments. Common areas for treatment include:
We usually recommend a course of 2–3 treatments, spaced a few weeks apart, for the best results. Many clients notice improvements in texture and hydration after the first session.
The treatment is generally well tolerated. A fine needle is used, and a numbing cream can be applied for extra comfort.
You may experience a little redness or mild swelling at the injection points, which usually settles within 24–48 hours. Most people return to normal activities straight away.
Results build gradually as your skin repairs itself. You can expect noticeable improvements in texture, elasticity, and overall radiance within a few weeks, with continued progress over several months.
The results typically last around 6–12 months, depending on your skin and lifestyle. Many clients choose to maintain results with top-up sessions once or twice a year.
Polynucleotides are especially effective for delicate areas such as the under-eyes, as well as the face, neck, décolletage, and hands.
Pairing your treatment with AlumierMD medical-grade skincare Helps protect and maintain your skin health, giving you longer-lasting results.
Polynucleotides can be used for target a specific area of the face, neck or body. For a small targeted area, for example around the eyes to treat dark circles, eye bags or crows feet, this is charged at £250. For full face rejuvenation or full neck this is £450. A course of 2-3 sessions is usually recommended, up to 4 for advanced ageing. Click book appointment to view the full price list or book a consultation to find out more.